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Abortion Pill Reversal (APR) is the process of attempting to reverse the effects of the first dose of the RU-486 pill, ( the abortion pill), by administering Progesterone through the 12^th week of pregnancy.  

Abortion Pill Reversal is only performed if a woman has NOT taken the second set of pills, and if it has been no longer than 72 hours since she took the first set of pills. APR is most effective if started within 24 hours of taking the first dose of RU-486.  

If you have changed your mind and want to continue with your pregnancy, you can call the APR Hotline at 1-877-558-0333 or Hands of Hope Tucson at 520-622-5774 and we will walk you through the next steps. 

How does it work? 

After a woman calls and expresses an interest in APR, our Pregnancy Medical Center staff will be available for an initial consultation with a registered nurse or nurse practitioner. Then we will schedule an appointment for a pregnancy test and ultrasound. 

The Ultrasound Nurse or Nurse Practitioner will determine if the pregnancy is viable by visualizing the baby and heartbeat. If the pregnancy is determined to be viable, the woman can begin the Oral Progesterone Protocol.  She will be administered a dose of Progesterone and will be given instructions on how to take it for the next week. If the client did not see a Nurse Practitioner at their first appointment, she will be scheduled for a follow-up appointment with a nurse practitioner within the next week.  

If the pregnancy continues, the client will visit us for weekly ultrasound appointments through the 12^th week of her pregnancy.  Arrangements will then be made for the client to see her OB Physician, who will continue her Prenatal Care through delivery. 

If you have taken the first dose of the RU-486 pill and you have changed your mind, call the APR Hotline at 1-877-558-0333 or Hands of Hope Tucson at 520-622-5774.

Abortion Pill Reversal has a success rate average of 68% for continuation of a healthy, viable  pregnancy.  If you have taken the first dose of the RU-486 pill and you have changed your mind, call the APR Hotline at 1-877-558-0333 or Hands of Hope Tucson at 520-622-5774 and we will assist you with your next steps. No matter what decision you make, we’re here to help you through it.  

References and More Information

• “ A Case Series Detailing the Successful Reversal of the Effects of Mifepristone Using Progesterone” 
• George Delgado, MD, Steven J. Condly, Ph.D., Mary Davenport, MD, MS., Thidarat Tinnakornsrisuphap Ph.D., Jonathan Mack, Ph.D., NP, RN, Veronica Khauv, B.S., and Paul S. Zhou 

• ^{[Vaux NW and Rakoff AE: Estrogen-progesterone therapy: A new approach in the treatment of habitual abortion. Am J Obst Gynec 50:353, 1945.} 
• ^{Jones, GES: Some newer aspects of the management of infertility. JAMA 141:1123, 1949.]↩} 
• ^{[Progesterone support in pregnancy has been in use for nearly 60 years, having received its start with publications dating back to the 1940s.] (https://www.naprotechnology.com/progesterone.htm)} 
• ^{[Progestin Therapy to Prevent Preterm Birth: History and Effectiveness of Current Strategies and Development of Novel Approaches] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6766339/} 
• ^{[The Use of Progesterone for Prevention of Preterm Birth] https://www.researchgate.net/publication/5653589_The_Use_of_Progesterone_for_Prevention_of_Preterm_Birth} 
• ^{[The history of natural progesterone, the never-ending story] https://tahomaclinic.com/Private/Articles1/BHRT/Piette%202018%20-%20The%20history%20of%20natural%20progesterone,%20the%20never-ending%20story.pdf}